glp-1 for obesity thibodaux GLP-1-based therapies diabetes, and beyond Some US employers to drop

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Phase 2 trial data (Jastreboff et al., NEJM 2023) demonstrated average weight reductions of approximately 1724% over 48 weeks notably higher than currently approved GLP-1 receptor agonists such as semaglutide, though direct comparisons are limited by differences in trial populations and designs

Although several selectin inhibitors have been tested in clinical trials for bronchial asthma patients, they have not proven to be effective

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Amino Acids 51:3948 Nakatani S, Mano H, Sampei C et al (2009) Chondroprotective effect of the bioactive peptide prolyl-hydroxyproline in mouse articular cartilage in vitro and in vivo